Cell Proliferation and Tissue Compatibility of Organic-Inorganic Hybrid Materials

When an artificial material is implanted or embedded in our body tissue, regardless of intentionally as clinical treatment or accidentally, it will inevitably get in contact with blood or blood plasma. As soon as the contact is established, all substance in blood and the cells of the contacting organ comes to the materials surface and is attached to find if the material is originated from the body or alien. Then, chemical, physical-chemical, and biological interactions or reactions take place at the material-tissue interface, which Fig. 1 schematically illustrates.