Water-soluble aldehyde-bearing polymers of 2-deoxy-2-methacrylamido-D-glucose for bone tissue engineering
In this study the methods of synthesis of hydrophilic aldehyde-bearing polymers and copolymers based on 2-deoxy-2-methacrylamido-D-glucose have been developed. Polymers with controllable aldehyde group content were synthesized via free-radical polymerization and subsequent polymeranalogous modificat...
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Veröffentlicht in: | Journal of applied polymer science 2008-05, Vol.108 (4), p.2386-2397 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | In this study the methods of synthesis of hydrophilic aldehyde-bearing polymers and copolymers based on 2-deoxy-2-methacrylamido-D-glucose have been developed. Polymers with controllable aldehyde group content were synthesized via free-radical polymerization and subsequent polymeranalogous modification. The water-soluble polymers obtained were investigated in view of their capacity to be adsorbed on two commercial mineral supports used in bone tissue engineering. Besides, cytotoxicity of synthesized polymers was tested. |
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ISSN: | 0021-8995 1097-4628 |
DOI: | 10.1002/app.27292 |