Toxicity of lapachol and isolapachol and their potassium salts against Biomphalaria glabrata, Schistosoma mansoni cercariae, Artemia salina and Tilapia nilotica

Toxicity of lapachol and isolapachol and their potassium salts against Biomphalaria glabrata, Schistosoma mansoni cercariae, Artemia salina and Tilapia nilotica

The toxicity of soluble derivatives (potassium salt) of lapachol and isolapachol in different stages of the life cycle of Schistosoma mansoni is evaluated. The potassium salts of isolapachol and lapachol showed significant molluscicidal activity against the adult snail (LC 90

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Bibliographische Detailangaben
Veröffentlicht in:Acta tropica 2002-07, Vol.83 (1), p.43-47
Hauptverfasser: Lima, Nadja Maria Fernandes, dos Santos, Aldenir Feitosa, Porfı́rio, Zenaldo, Goulart, Marı́lia O.F, Sant'Ana, Antônio Euzébio G
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Anthelmintics - toxicity
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiparasitic agents
Artemia - drug effects
Biological and medical sciences
Biomphalaria - drug effects
Biomphalaria glabrata
Cercaricide
Confidence Intervals
Isolapachol potassium salt
Lapachol potassium salt
Medical sciences
Molluscacides - toxicity
Naphthoquinones - toxicity
Parasitic Sensitivity Tests
Pharmacology. Drug treatments
Piscicide
Schistosoma mansoni - drug effects
Snail control
Structure-Activity Relationship
Tilapia
Tropical medicine
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Zusammenfassung:The toxicity of soluble derivatives (potassium salt) of lapachol and isolapachol in different stages of the life cycle of Schistosoma mansoni is evaluated. The potassium salts of isolapachol and lapachol showed significant molluscicidal activity against the adult snail (LC 90
ISSN:0001-706X
1873-6254
DOI:10.1016/S0001-706X(02)00055-4