Self-Assembly of Cell-Microparticle Hybrids

Self-Assembly of Cell-Microparticle Hybrids

Synthetic‐biological hybrids of biodegradable microparticles and transfected cells are assembled, as schematically illustrated in the figure. The cells are surface‐functionalized with biotin and the particle surface is also engineered with biotin. Avidin is then used as a bridging protein to bind to...

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Veröffentlicht in:Advanced materials (Weinheim) 2008-03, Vol.20 (5), p.989-993
Hauptverfasser: Krishnamachari, Y., Pearce, M. E., Salem, A. K.
Format: Artikel
Sprache:eng
Schlagworte:
Biotin
Cells
Hybrid materials
Self-assembly
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Beschreibung
Zusammenfassung:Synthetic‐biological hybrids of biodegradable microparticles and transfected cells are assembled, as schematically illustrated in the figure. The cells are surface‐functionalized with biotin and the particle surface is also engineered with biotin. Avidin is then used as a bridging protein to bind together the microparticles and the surface‐ functionalized cells.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200701689