Green chemical approaches and tools in the development of environmentally friendly synthetic methods

Addressing the recommendations of the 12 basic lows of green chemistry, the microwave technique was utilized in phospha-Mannich, Diels-Alder and inverse Wittig type reactions, moreover under solventless conditions. In the phase transfer catalysed alkylation of CH-acidic compounds, the quaternary onium salts could be substituted by MW irradiation. The effect of chiral phase transfer catalysts was compared on suitable, potentially enantioselective model reactions. Mono- and bidental P-ligands were developed to make available novel platinum complexes that can be useful as catalysts. Finally, esterifications including diesterifications were studied by in situ Fourier Transform IR spectroscopy.