Morphology of Microtubules Grown in Agarose Gels: Effect of Diffusion and Confinement

Morphology of Microtubules Grown in Agarose Gels: Effect of Diffusion and Confinement

The controlled assembly of active microtubule (MT)‐based networks offers great promise in numerous technologies. The design and construction of these systems requires MT growth in 3D scaffolds such as gels. We report on the morphology of MTs grown in a crowded environment in the form of viscous flui...

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Veröffentlicht in:Advanced materials (Weinheim) 2008-01, Vol.20 (1), p.183-188
Hauptverfasser: Castro, J. S., Deymier, P. A., Smith, S. D., Hoying, J. B.
Format: Artikel
Sprache:eng
Schlagworte:
Biomaterials
Microtubes
Nanostructures
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Zusammenfassung:The controlled assembly of active microtubule (MT)‐based networks offers great promise in numerous technologies. The design and construction of these systems requires MT growth in 3D scaffolds such as gels. We report on the morphology of MTs grown in a crowded environment in the form of viscous fluids containing agarose, and in confined environments in the case of solid agarose gels. The experimental results are supported by a computational model.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200700608