Prevalence of hypodontia and other developmental dental anomalies in children with or without molar incisor hypomineralisation

To investigate whether hypodontia and other developmental dental anomalies were more common in children with MIH than their unaffected peers, and to determine if sex or geographical location had any effect on hypodontia prevalence.OBJECTIVESTo investigate whether hypodontia and other developmental dental anomalies were more common in children with MIH than their unaffected peers, and to determine if sex or geographical location had any effect on hypodontia prevalence.This analytical cross-sectional study was conducted in specialist paediatric dentistry clinics across 14 countries, categorised into six geographical regions. A total of 1279 children (aged 6 - 17 years) underwent a clinical examination and were allocated to the MIH (n = 649) or comparison group (n = 630). A validated MIH index was used to record the presence/extent of any hypomineralisation and a standardised approach was used to establish the clinical and/or radiographic presence of ten DDAs.METHODSThis analytical cross-sectional study was conducted in specialist paediatric dentistry clinics across 14 countries, categorised into six geographical regions. A total of 1279 children (aged 6 - 17 years) underwent a clinical examination and were allocated to the MIH (n = 649) or comparison group (n = 630). A validated MIH index was used to record the presence/extent of any hypomineralisation and a standardised approach was used to establish the clinical and/or radiographic presence of ten DDAs.Four anomalies were significantly more prevalent in participants with MIH than those without this condition: hypodontia (p=0.047), dens invaginatus (p=0.004), dens evaginatus (p