Real-world efficacy and safety of universal 8-week glecaprevir/pibrentasvir in patients with chronic hepatitis C with early chronic kidney disease or pre-end-stage renal disease: Insights from a nationwide hepatisis C virus registry in Taiwan

Real-world efficacy and safety of universal 8-week glecaprevir/pibrentasvir in patients with chronic hepatitis C with early chronic kidney disease or pre-end-stage renal disease: Insights from a nationwide hepatisis C virus registry in Taiwan

An 8-week regimen of glecaprevir/pibrentasvir is recommended for treatment-naïve patients with chronic hepatitis C (CHC). In alignment with the Taiwanese government's objective to eliminate hepatitis C by 2025, this study aimed to provide real-world evidence on the use of this regimen in treatm...

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Veröffentlicht in:The Kaohsiung journal of medical sciences 2025-01, p.e12929
Hauptverfasser: Wang, Szu Jen, Huang, Chung-Feng, Chang, Te Sheng, Lo, Ching Chu, Hung, Chao Hung, Huang, Chien Wei, Chong, Lee Won, Cheng, Pin Nan, Yeh, Ming Lun, Peng, Cheng Yuan, Cheng, Chien Yu, Huang, Jee Fu, Bair, Ming Jong, Lin, Chih Lang, Yang, Chi Chieh, Kuo, Hsing Tao, Hsieh, Tsai Yuan, Lee, Tzong Hsi, Lee, Pei Lun, Wu, Wen Chih, Lin, Chih Lin, Su, Wei Wen, Yang, Sheng Shun, Wang, Chia Chi, Hu, Jui Ting, Mo, Lein Ray, Chen, Chun Ting, Huang, Yi Hsiang, Chang, Chun Chao, Huang, Chia Sheng, Chen, Guei Ying, Kao, Chien Neng, Tai, Chi Ming, Liu, Chun Jen, Lee, Mei Hsuan, Tsai, Pei Chien, Dai, Chia Yen, Kao, Jia Horng, Lin, Han Chieh, Chuang, Wang Long, Tseng, Kuo Chih, Chen, Chi Yi, Wang, Shu-Chi, Yu, Ming-Lung
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Sprache:eng
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Zusammenfassung:An 8-week regimen of glecaprevir/pibrentasvir is recommended for treatment-naïve patients with chronic hepatitis C (CHC). In alignment with the Taiwanese government's objective to eliminate hepatitis C by 2025, this study aimed to provide real-world evidence on the use of this regimen in treatment-naïve patients with chronic kidney disease (CKD) by using data from the Taiwan Association for the Study of the Liver HCV Registry (TACR). CKD was defined by an estimated glomerular filtration rate (eGFR) of
ISSN:1607-551X
2410-8650
2410-8650
DOI:10.1002/kjm2.12929