Bifenthrin causes disturbance in mitochondrial dynamics and bioenergetic system in human embryonic kidney cells (HEK 293)

[Display omitted] •BF causes cytotoxicity in human kidney cells and triggering apoptotic cell death.•BF exposure significantly increased ROS generation, reduced mitochondrial membrane potential.•BF altered gene expression of fusion and fission disrupting mitochondrial dynamics.•BF exposure caused si...

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Veröffentlicht in:	Environmental pollution (1987) 2025-01, Vol.368, p.125707, Article 125707
Hauptverfasser:	Das, Anwesha, Das, Madhusudan, Paul, Nirvika, Chatterjee, Srilagna, Sarkar, Kunal, Bank, Sarbashri, Sarkar, Jit, Bankura, Biswabandhu, Roy, Debraj, Acharya, Krishnendu, Ghosh, Sudakshina
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Zusammenfassung:	[Display omitted] •BF causes cytotoxicity in human kidney cells and triggering apoptotic cell death.•BF exposure significantly increased ROS generation, reduced mitochondrial membrane potential.•BF altered gene expression of fusion and fission disrupting mitochondrial dynamics.•BF exposure caused significant disruption of the mitochondrial branched network.•BF affected mitochondrial respiratory capacity in human kidney cells.
ISSN:	0269-7491 1873-6424 1873-6424
DOI:	10.1016/j.envpol.2025.125707