Copper functionalized, pro-angiogenic, and skin regenerative scaffolds based on novel chitosan/APDEMS modified sepiolite-based formulation

Biomaterials-based scaffolds are extensively explored for their proangiogenic and tissue regenerative abilities. The present study aimed to develop wound healing scaffolds based on chitosan/aminopropyldiethoxymethylsilane (APDEMS) modified sepiolite, loaded with copper (0–0.25 g), characterized by F...

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Veröffentlicht in:	International journal of biological macromolecules 2024-12, Vol.283 (Pt 1), p.137538, Article 137538
Hauptverfasser:	Gull, Aysha, Hussain, Tajamal, Islam, Atif, Ara, Chaman
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Animals biocompatible materials Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Biocomposites CAM assay Chick Embryo chicks chitosan Chitosan - chemistry Chitosan - pharmacology collagen copper Copper - chemistry crosslinking excision histology histopathology In vivo toxicity Magnesium Silicates - chemistry Mice modulus of elasticity Neovascularization, Physiologic - drug effects Regeneration - drug effects Scaffolds sepiolite Silanes - chemistry Skin - drug effects Skin regeneration Tissue Engineering - methods Tissue Scaffolds - chemistry toxicity Wound Healing - drug effects
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