Beyond plastic pollution: Unveiling chemical release from plastic debris in river water and seawater using non-target screening

•Chemical release from PVC particles in water reached pseudo-equilibrium within 30d•Dissolved organic matter and weathering of plastics enhanced chemical releases.•Metal ions in river water potentially hindered chemical release from plastics.•Thousands of unknown chemicals would be released from plastics once entering waters.•Released chemicals from plastics in waters showed product- and matrix-dependence. Oceans and rivers are predominant sinks, reservoirs, and carriers of plastic debris that are proposed to be long term sources of a variety of contaminants in the environments. This research unveiled kinetics of chemical releases from plastic debris in freshwater and marine environment via artificial river water (ARW) and seawater (ASW) in combination of nontarget screening. Chemical leaching from PVC cord particles in the ARW and ASW basically followed the first order kinetics, reaching pseudo-equilibrium in 30d and 14d, respectively, associated with both particle surface – water partitioning and inner-particle diffusion of chemicals. Dissolved organic carbon, finer size, and weathering of plastic particles might enhance whereas metal ions potentially hinder chemical releases from plastic debris in waters, respectively. Salinity and pH showed moderate effects on chemical leaching. In addition, chemicals’ physiochemical properties might also affect their leaching behavior. Hundreds to thousands of chemicals would be released from plastic debris in days once entering waters, among which > 80% were unknown with rare or no information about eco-toxicity and environmental fate, posing unpredicted risks to the environment. Furthermore, new chemicals may keep being released with increasing weathering and extending retention time of plastics in waters, leading to increases in both numbers and complexities of released chemicals. Chemical leaching from plastics showed product-dependence and certain differences in freshwater and seawater. Large numbers of unknown chemicals potentially released from plastic debris in rivers, lakes, and oceans and subsequent environmental risks warrant in-depth research. [Display omitted]