Feasibility of MoS2 for analytical and bioanalytical applications

Molybdenum disulfide (MoS2) received recognition from the scientific community due to its high absorbance in the NIR region, superior physiological and biocompatibility traits, high fluorescence quenching ability, and fluorescence emission feature, making it suitable for analytical and bioanalytical applications. In this review, we highlighted salient traits of MoS2 that accelerate its feasibility for analytical sciences. The particular bandgap of 1.8 eV in its monolayers and layer-dependence of band structures tackle the gapless problems of graphene, enhancing its scientific and industrial importance. The characteristic electronic structure and low cyto- and genotoxicity profiles, tunable structure, and surface functionalization of MoS2 compared to other transition metal dichalcogenides render it feasible for next-generation optoelectronics, analytical, biomedical, and point-of-care applications. To fully unleash the potential of MoS2 for commercial implementation, the era demands to fabrication of facile, cost-effective, and tunable synthesis approaches, exploring their structure-activity relationship, and investigating their stability, biocompatibility, and toxicology profiles. •Salient features of MoS2 for analytical and bioanalytical applications are reviewed.•Structural and electronic states of MoS2 navigate its particular applications.•Tunable synthesis and detailed analyses can fully unleash MoS2 for commercial use.