Ullmann coupling reaction of dihalobenzenes and malononitrile-heterocumulene adducts under ultrasound-irradiation

In this study, various benzothiazoles, benzoxazoles, and benzo[1,3]-dithiols derivatives with good yields were obtained using the Ullmann coupling reaction of dihalobenzenes and malononitrile-heterocumulene adducts in the vicinity of copper catalyst, Cs2CO3 as a base under ultrasound irradiation. The use of the popular sonochemical method, short reaction time, simple and available raw materials, mild catalytic copper reaction conditions, simple purification, and good efficiency are some of the notable characteristics of this protocol. [Display omitted] •Novel protocols synthesis of various benzothiazoles, benzoxazoles, and benzo[1,3]-dithiols.•CuI catalyzed and efficient sonochemical method in the synthesis of benzothiazoles, benzoxazoles and benzo[1,3]-dithiols.•Ullmann coupling reaction of dihalobenzene and malononitrile-heterocumulene adducts.