A template-based approach to the synthesis of 1,7-dioxaspiro[5.5]undecane spiroketal derivatives

This work investigates the preparation of 1,7-dioxaspiro [5.5]undecane derivatives via the application of the template compound 2,8-bis(bromomethyl)-1,7-dioxaspiro [5.5]undecane and a series of catalysed carbonyl-ene reactions introducing aromatic and non-aromatic linkers to the heterocyclic system,...

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Veröffentlicht in:	Tetrahedron 2023-06, Vol.140, p.133454, Article 133454
Hauptverfasser:	Sheng, Li, Bhalla, Rajiv
Format:	Artikel
Sprache:	eng
Schlagworte:	catalytic activity Cyclization Ene reaction heterocyclic compounds Hydrolysis Lewis acids Natural products Spiro compounds toxins
Online-Zugang:	Volltext
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