Interactions between lipid metabolism and the microbiome in aquatic organisms: A review

Marine organisms' lipid metabolism contributes to marine ecosystems by producing a variety of lipid molecules. Historically, research focused on the lipid metabolism of the organisms themselves. Recent microbiome studies, however, have revealed that gut microbial communities influence the amount and type of lipids absorbed by organisms, thereby altering the organism's lipid metabolism. This has highlighted the growing importance of research on gut microbiota. This review highlights mechanisms by which gut microbiota facilitate lipid digestion and diversify the lipid pool in aquatic animals through the accelerated degradation of exogenous lipids and the transformation of lipid molecules. We also assess how environmental factors and pollutants, along with the innovative use of probiotics, interact with the gut microbiome to influence lipid metabolism within the host. We aim to elucidate the complex interactions between lipid metabolism and gut microbiota in aquatic animals by synthesizing current research and identifying knowledge gaps, providing a foundation for future explorations. [Display omitted] •The gut microbiota of aquatic animals release lipases to breakdown and absorb lipids.•Microbiota metabolize primary bile acids.•Desaturase and elongase activity alter fatty acid profiles.•Gut microbiota make SCFAs from indigestible carbohydrates.•Environmental variables alter gut microbiome.