Enzymatic degradation of synthetic plastics by hydrolases/oxidoreductases

Synthetic plastics and microplastics are naturally difficult to degrade due to their stable structure of high molecular weight, which are increasingly serious pollution to the environment. Recent findings have presented the existence of enzymes capable of degrading synthetic plastics. The use of enzymes to degrade plastics is environmentally friendly and has great application potential for future engineering. Therefore, considering the recent advancements in this research field, this review highlights enzymes of hydrolases/oxidoreductases for biodegradation of synthetic plastics with their degradation mechanisms. Furthermore, This review provides an extraordinarily detailed insight into influence of intrinsic properties of plastics and enzymes and external environment on enzymatic degradation process. Furthermore, evaluation methods for enzymatic degradation on synthetic plastics were discussed. Finally, perspective for future research to improve innovation in plastic degradation and recycling technology, empowers the development and utilization of biodegradable plastics. [Display omitted] •The use of enzymes to degrade plastics is environmentally friendly for future engineering.•Various enzymes have exhibited plastic-degrading abilities.•Enzymatic adsorption oxidation/hydrolysis degrades plastics to low molecular weight.•Several challenges in the biodegradation of plastics remain to be addressed.