Rapid determination of quercetin and caffeic acid in honeysuckle tea by high efficiency electrochemical sensor

This research elucidates the enhanced electrochemical performance of a sensor, utilizing multi-walled carbon nanotubes (MWCNT) modified with Au and 2,6-dioctadecylaminopyridine (DODMA) for the detection of quercetin and caffeic acid. The study highlights the importance of electrode modifications, indicating that MWCNT-Au and DODMA noticeably boost the sensor’s electroactivity. For quercetin detection, an optimal pH of 4, an enrichment potential of 0.28 V, and an enrichment time of 15 min were established. For caffeic acid, the sensor showed optimum performance at pH 2.20. Moreover, the sensor demonstrated excellent linearity within two distinct ranges of caffeic acid concentration (0.005-5 µM and 6–50 µM). The DPV method showed recovery rates ranging from 98.20 to 102.42% for quercetin and 99.51–99.82% for caffeic acid in honeysuckle tea, underscoring the sensor’s precision and reliability. The promising results of this study show potential applications for this sensor platform in the detection of other bioactive compounds.