Clinical value of CEUS with tumour marker monitoring in evaluating the prognosis of HCC after MWA

This study aims to evaluate the prognostic value of contrast-enhanced ultrasound (CEUS) combined with tumour markers in patients with hepatocellular carcinoma (HCC) undergoing microwave ablation (MWA). MWA patients with HCC were divided into good prognosis (n ​= ​75) and poor prognosis (n ​= ​69) gr...

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Veröffentlicht in:Advances in medical sciences 2025-03, Vol.70 (1), p.79-85
Hauptverfasser: Guo, Qiang, Yu, Yang, Ye, Ruyun, Huang, Zhiliang, Shi, Tingting
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Sprache:eng
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Zusammenfassung:This study aims to evaluate the prognostic value of contrast-enhanced ultrasound (CEUS) combined with tumour markers in patients with hepatocellular carcinoma (HCC) undergoing microwave ablation (MWA). MWA patients with HCC were divided into good prognosis (n ​= ​75) and poor prognosis (n ​= ​69) groups. The levels of alpha-fetoprotein (AFP), carbohydrate antigen (CA19-9), and carcinoembryonic antigen (CEA) before and after MWA were analysed using an independent sample t-test. The correlation between prognosis, ablation lesion area, and tumour marker levels were analysed by Pearson's correlation. The diagnostic power of the ablation lesion area combined with tumour marker levels for the prognosis of patients with MWA was analysed using receiver operating characteristic (ROC) curves. The levels of AFP, CA19-9, and CEA in the good prognosis group were significantly lower than those in the poor prognosis group (all P ​
ISSN:1896-1126
1898-4002
1898-4002
DOI:10.1016/j.advms.2025.01.001