Disease control and quality of life in chronic spontaneous urticaria and recurrent angioedema are strongly linked, but not in all patients

Patient-reported outcome measures (PROMs) help to assess disease control and quality of life (QoL) in chronic spontaneous urticaria (CSU) and recurrent angioedema (RA). This study aimed to assess the correlation between two different concepts: disease control and QoL, using disease-specific PROMs. We analyzed data from 445 CSU and 330 RA patients who completed both a disease control and QoL PROM as part of the clinical routine. We included the UCT and CU-Q2oL for CSU and AECT and AE-QoL for RA. In CSU and RA, disease control scores positively correlated with QoL scores (Spearman's rho correlation coefficient (CR) -0.757, -0.735; p