A risk-based approach can guide safe cell line development and cell banking for scaled-up cultivated meat production

For commercial viability, cultivated meats require scientifically informed approaches to identify and manage hazards and risks. Here we discuss food safety in the rapidly developing field of cultivated meat as it shifts from lab-based to commercial scales. We focus on what science-informed risk mitigation processes can be implemented from neighbouring fields. We case-study pre-market safety assessments from UPSIDE Foods, GOOD Meat and Vow Group using publicly available dossiers. Quality control and safety assurance practices need to be established and standardized for cell lines and food-grade cell banks. Safe and reliable cell sources are essential for cultivated meat production. This Perspective explores approaches from fields using similar technologies and pre-market dossiers to address food safety issues associated with scale-up and commercial viability.