Ginkgolic acid inhibits Ebola virus transcription and replication by disrupting the interaction between nucleoprotein and VP30 protein

The Ebola virus, a filovirus, has been responsible for significant human fatalities since its discovery. Despite extensive research, effective small-molecule drugs remain elusive due to its complex pathogenesis. Inhibition of RNA synthesis is a promising therapeutic target, and the VP30 protein play...

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Veröffentlicht in:	Antiviral research 2025-02, Vol.234, p.106074, Article 106074
Hauptverfasser:	Peng, Chiwei, Wu, Fang, Ma, Yanhong, Liu, Guolong, Huang, Yin, Tong, Rongbiao, Xu, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystal structure Ebola virus Ginkgolic acid VP30
Online-Zugang:	Volltext
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