CMR-BENet: A confidence map refinement boundary enhancement network for left ventricular myocardium segmentation

Left ventricular myocardium segmentation is of great significance for clinical diagnosis, treatment, and prognosis. However, myocardium segmentation is challenging as the medical image quality is disturbed by various factors such as motion, artifacts, and noise. Its accuracy largely depends on the accurate identification of edges and structures. Most existing encoder–decoder based segmentation methods capture limited contextual information and ignore the awareness of myocardial shape and structure, often producing unsatisfactory boundary segmentation results in noisy scenes. Moreover, these methods fail to assess the reliability of the predictions, which is crucial for clinical decisions and applications in medical tasks. Therefore, this study explores how to effectively combine contextual information with myocardial edge structure and confidence maps to improve segmentation performance in an end-to-end network. In this paper, we propose an end-to-end confidence map refinement boundary enhancement network (CMR-BENet) for left ventricular myocardium segmentation. CMR-BENet has three components: a layer semantic-aware module (LSA), an edge information enhancement module (EIE), and a confidence map-based refinement module (CMR). Specifically, LSA first adaptively fuses high- and low-level semantic information across hierarchical layers to mitigate the bias of single-layer features affected by noise. EIE then improves the edge and structure recognition by designing the edge and mask guidance module (EMG) and the edge structure-aware module (ESA). Finally, CMR provides a simple and efficient way to estimate confidence maps and effectively combines the encoder features to refine the segmentation results. Experiments on two echocardiography datasets and one cardiac MRI dataset show that the proposed CMR-BENet outperforms its rivals in the left ventricular myocardium segmentation task with Dice (DI) of 87.71%, 79.33%, and 89.11%, respectively. This paper utilizes edge information to characterize the shape and structure of the myocardium and introduces learnable confidence maps to evaluate and refine the segmentation results. Our findings provide strong support and reference for physicians in diagnosis and treatment. •Introducing CMR-BENet: A novel network for left ventricular myocardium segmentation.•LSA: Enhances the ability to capture contextual information.•EIE: Improves the awareness of edge and structure.•CMR: Calculates confidence maps in a simple way and re