Sex and Gender Differences in Weight-Related Biopsychosocial Factors Among Adults Receiving Buprenorphine for Opioid Use Disorder

Medication for opioid use disorder (MOUD) is the most efficacious treatment for opioid use disorder (OUD). MOUD uptake and continuation may be impacted by health concerns, including weight gain, and social factors, such as food insecurity, that vary between men and women. This study aimed to describe sex and gender differences in body mass index (BMI) and weight-related demographic, psychosocial, and clinical characteristics among adults receiving buprenorphine for OUD. This secondary analysis used data from a cross-sectional survey and prospective medical record review study among adults (n = 77 female, n = 66 male) engaged in outpatient treatment receiving buprenorphine for OUD. Survey items assessed weight-related demographic and psychosocial variables. Clinical factors were collected via chart abstraction. Comparisons between male and female participants were made using χ , Mann Whitney , and -tests. Most participants were non-Latinx, Black (69.9%), with a mean age of 43.3 ± 12.3 years. Among females, 2.6% had a BMI