Oxygen Delivery During Cardiopulmonary Bypass in Pediatric Patients With Congenital Heart Disease: Association With Postoperative Acute Kidney Injury

•Oxygen supply to organs (DO2) depends on blood flow and oxygen content.•The association between DO2 during bypass and acute kidney injury is not significant.•Low DO2 during bypass is significantly associated with high serum lactate levels. This study was designed to investigate the distribution of...

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Veröffentlicht in:Journal of cardiothoracic and vascular anesthesia 2024-11
Hauptverfasser: Taka, Hiroshi, Douguchi, Takuma, Miyamoto, Ayako, Shimizu, Kazuyoshi, Iwasaki, Tatsuo, Kanazawa, Tomoyuki, Kimura, Satoshi, Morimatsu, Hiroshi
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Sprache:eng
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Zusammenfassung:•Oxygen supply to organs (DO2) depends on blood flow and oxygen content.•The association between DO2 during bypass and acute kidney injury is not significant.•Low DO2 during bypass is significantly associated with high serum lactate levels. This study was designed to investigate the distribution of nadir oxygen delivery (DO2), mean DO2, and area under ideal DO2 (AUiDO2) among categorized age groups of pediatric patients and their associations with postoperative cardiac surgery–associated (CSA) acute kidney injury (AKI) and clinical outcomes. Retrospective cohort study. A tertiary teaching hospital. Patients aged
ISSN:1053-0770
1532-8422
1532-8422
DOI:10.1053/j.jvca.2024.11.017