Endovascular thrombectomy for acute ischemic stroke complicated with systemic light chain amyloidosis: Two case reports

Systemic light chain amyloidosis (AL) is a non-proliferative plasma cell disease characterized by the deposition of fragments of immunoglobulin light or heavy chain in tissues. There has been no relevant report on the treatment of vascularization during the acute stage of acute ischemic stroke (AIS)...

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Veröffentlicht in:Journal of stroke and cerebrovascular diseases 2025-02, Vol.34 (2), p.108181, Article 108181
Hauptverfasser: Bai, Yongjie, Sun, Bingjie, Su, Jiahui
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Sprache:eng
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Zusammenfassung:Systemic light chain amyloidosis (AL) is a non-proliferative plasma cell disease characterized by the deposition of fragments of immunoglobulin light or heavy chain in tissues. There has been no relevant report on the treatment of vascularization during the acute stage of acute ischemic stroke (AIS) complicated with AL. This paper presented two cases of AIS complicated with AL that were treated with intravenous thrombolysis (IVT) and mechanical thrombectomy (MT). The combination of aspiration thrombectomy and IVT might be feasible for patients with AIS complicated with AL.
ISSN:1052-3057
1532-8511
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2024.108181