The universal Rhs shell structure accommodates various toxins inside and different functional decorations on the outside

In this issue of Structure, Kielkopf et al.1 report the crystal structures of Rhs proteins that are genetically fused to the type VI secretion system PAAR or VgrG proteins. The work highlights the structural similarities of Rhs proteins despite diverse decorations surrounding the Rhs core and different delivery modes. In this issue of Structure, Kielkopf et al. report the crystal structures of Rhs proteins that are genetically fused to the type VI secretion system PAAR or VgrG proteins. The work highlights the structural similarities of Rhs proteins despite diverse decorations surrounding the Rhs core and different delivery modes.