A Case Report of an Osteolytic Mass Hiding Behind an Undiagnosed Parathyroid Adenoma

Hyperparathyroidism is a common endocrinopathy classified into three subtypes: primary, secondary, and tertiary. One of the rare symptoms that patients with hyperparathyroidism present is the formation of osteolytic lesions of the jaws. Brown tumors are rare skeletal osteolytic masses of a poorly un...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2024-11, Vol.16 (11), p.e74762
Hauptverfasser: Al Olaimat, Mohammed S, Al Qooz, Fahad S, Alzoubi, Zaid R, Alsharaiah, Elham M, Alqahtani, Abdulkarim M
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Sprache:eng
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Zusammenfassung:Hyperparathyroidism is a common endocrinopathy classified into three subtypes: primary, secondary, and tertiary. One of the rare symptoms that patients with hyperparathyroidism present is the formation of osteolytic lesions of the jaws. Brown tumors are rare skeletal osteolytic masses of a poorly understood etiology. These tumors are usually caused by a mutation in the CDC73 gene, a tumor suppressor protein gene that translates to parafibromin. Treatment has been reported to range from a conservative parathyroidectomy to resection and reconstruction. We present a case of a female who presented with a facial disfigurement for four months that was hidden under the effect of a parathyroid adenoma. Our aim is to guide the surgeon in the proper detailed management of osteolytic lesions of jaws that are related to parathyroid hyperfunction.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.74762