Whole milk intake is associated with lower body weight and body mass index in American adults

•Average whole milk intake was 1.0 to 1.4 cups eq/d among consumers.•Whole milk intake was inversely associated with weight, BMI, and the prevalence of obesity.•Whole milk intake was also positively associated with desire to lose weight. The objective was to determine if whole milk intake or total milk intake behaviors are associated with body weight (weight) and related parameters in adults. We hypothesize that whole milk intake would be inversely associated with body weight measures. Whole milk (including flavored whole milk) intake was assessed using 24-hour dietary recall data of the National Health and Nutrition Examination Survey 2001-2018 for adults age 20+ years (N = 43,038). Weight and related parameters were measured, and history of self-reported weights and total milk intake were obtained from questionnaire data. The association of whole milk intake with weight was assessed via regression after adjusting for demographic and lifestyle-related covariates. The average body mass index (BMI) was about 29 kg/m2 and weight was 76 to 89 kg. About 66% of the population were overweight or obese. Average whole milk intake among consumers was 1.0 to 1.4 cups eq/d. Whole milk intake was inversely associated (P < .05) with weight, BMI, waist circumference, and the prevalence of obesity. Whole milk intake was also inversely associated (P < .01) with trying to lose weight in the past year. In most cases, milk intake behavior at ages 5 to 12, 13 to 17, or 18 to 35 years was not associated with BMI. The results indicate that whole milk intake was inversely associated with weight, BMI, and prevalence of obesity, and these findings may provide additional evidence to support dietary recommendations for whole milk. Whole milk intake is inversely associated with body weight-related measures (value/cup eq) among gender-combined adults age 20+ years, NHANES 2001-2018 data. [Display omitted]