Standard or Extended Lymphadenectomy for Muscle-Invasive Bladder Cancer

In patients with muscle-invasive bladder cancer, extended lymphadenectomy did not improve disease-free or overall survival as compared with the standard procedure and was associated with higher morbidity and mortality.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2024-10, Vol.391 (13), p.1206-1216
Hauptverfasser:	Lerner, Seth P., Tangen, Catherine, Svatek, Robert S., Daneshmand, Siamak, Pohar, Kamal S., Skinner, Eila, Schuckman, Anne, Sagalowsky, Arthur I., Smith, Norm D., Kamat, Ashish M., Kassouf, Wassim, Plets, Melissa, Bangs, Rick, Koppie, Theresa M., Alva, Ajjai, La Rosa, Francisco G., Pal, Sumanta K., Kibel, Adam S., Canter, Daniel J., Thompson, Ian M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bladder cancer Cancer therapies Chemotherapy Chemotherapy, Adjuvant Coronary vessels Cystectomy - adverse effects Cystectomy - methods Death Disease-Free Survival Dissection Female Genitourinary Cancer Hematology Humans Invasiveness Kaplan-Meier Estimate Lymph Node Excision - adverse effects Lymph Node Excision - methods Lymph nodes Lymphatic Metastasis - pathology Lymphatic Metastasis - therapy Lymphatic system Male Metastasis Middle Aged Morbidity Mortality Neoadjuvant Therapy Neoplasm Invasiveness Neoplasm Staging Oncology Patients Pelvis Prostate Disease Prostate Disease General Surgeons Surgery Surgery General Survival Treatments in Oncology Urinary Bladder Neoplasms - mortality Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - therapy Urological surgery Urology Veins & arteries
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Beschreibung
Zusammenfassung:	In patients with muscle-invasive bladder cancer, extended lymphadenectomy did not improve disease-free or overall survival as compared with the standard procedure and was associated with higher morbidity and mortality.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2401497