Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG-AP) patients undergoing double filtration plasmapheresis (DFPP). A retrospective analysis of 82 HTG-AP-interpreted patients from January 2019 to April 2024 compared target plasma volume treated between up-to-scratch and non-scratch groups. The group comparison used independent samples t-test, Mann-Whitney U-test, and chi-square test. Binary logistic regression was used to identify independent risk factors for patients' plasma volume target failure. The ROC curve assessed these risk factors' diagnostic efficacy. Of 82 patients, 52 were classified as belonging to the up-to-scratch group, while the remaining 30 were classified as belonging to the non-to-scratch group. Statistically significant differences were seen between the groups regarding admission heart rate, triglyceride, calcitonin gene, C-reactive protein, D-dimer, and fibrinogen (FIB) levels (p