Anti-biofilm activity of carvacrol-thymoquinone nanocarriers on vulvovaginal candidiasis isolates

•The nanocarrier was spherical in shape and had a diameter of 50 nm.•The geometric mean of the minimum inhibitory concentration (MIC) of carvacrol-thymoquinone combination in free and nanocarrier forms was significantly lower than that of nystatin nanocarrier (P

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Bibliographische Detailangaben
Veröffentlicht in:	Diagnostic microbiology and infectious disease 2025-02, Vol.111 (2), p.116606, Article 116606
Hauptverfasser:	Hajiaghaalizadeh, Maryam, Sheikharabi, Mehdi, Jazi, Marie Saghaeian, Alhashem, Raheleh, Hosseini, Seyedeh Sedigheh
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - pharmacology Benzoquinones - chemistry Benzoquinones - pharmacology Biofilms - drug effects Candida - drug effects Candida albicans - drug effects Candida glabrata - drug effects Candidiasis, Vulvovaginal - drug therapy Candidiasis, Vulvovaginal - microbiology Carvacrol Cymenes - pharmacology Drug Carriers - chemistry Female Humans Microbial Sensitivity Tests Monoterpenes - chemistry Monoterpenes - pharmacology Nanoparticles - chemistry Nystatin Thymoquinone Vulvovaginal candidiasis
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Zusammenfassung:	•The nanocarrier was spherical in shape and had a diameter of 50 nm.•The geometric mean of the minimum inhibitory concentration (MIC) of carvacrol-thymoquinone combination in free and nanocarrier forms was significantly lower than that of nystatin nanocarrier (P
ISSN:	0732-8893 1879-0070 1879-0070
DOI:	10.1016/j.diagmicrobio.2024.116606