Basal ganglia: Uniting circuit logic between matrix and striosome

A new study has identified a novel direct–indirect circuit architecture connecting the striosome compartment of the striatum with midbrain dopamine neurons. This circuit has the potential to integrate limbic and sensorimotor functions and to exert substantial control over biological reinforcement leaning. A new study has identified a novel direct–indirect circuit architecture connecting the striosome compartment of the striatum with midbrain dopamine neurons. This circuit has the potential to integrate limbic and sensorimotor functions and to exert substantial control over biological reinforcement leaning.