Update to RIFM fragrance ingredient safety assessment, diethyl malonate, CAS registry number 105-53-3

•Diethyl malonate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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Veröffentlicht in:Food and chemical toxicology 2024-12, Vol.194, p.115113, Article 115113
Hauptverfasser: Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Friedrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.
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Sprache:eng
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Zusammenfassung:•Diethyl malonate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.
ISSN:0278-6915
1873-6351
1873-6351
DOI:10.1016/j.fct.2024.115113