Safety and efficacy of moderate-intensity statin plus ezetimibe versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease: A meta-analysis

Safety and efficacy of moderate-intensity statin plus ezetimibe versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease: A meta-analysis

•Compared moderated intensity statins (MIS) +Ezetimibe (EZT) with high intensity statins (HIS) in ASCVD. All the lastest meta-analysis included low/moderated intensity statins + ezetimibe versus high intensity statins.•MIS+EZT achieved greater LDL reduction than HIS.•There were no signifficant diffe...

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Veröffentlicht in:Journal of clinical lipidology 2024-08
Hauptverfasser: Kelly, Francinny Alves, de Moraes, Francisco Cezar Aquino, Lôbo, Artur de Oliveira Macena, Siebel, Victória Morbach, Leite, Marianna, de Almeida, Artur Menegaz, Consolim-Colombo, Fernanda Marciano
Format: Artikel
Sprache:eng
Schlagworte:
ASCVD
Ezetimibe
High-intensity statins
Moderate-intensity statins
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Zusammenfassung:•Compared moderated intensity statins (MIS) +Ezetimibe (EZT) with high intensity statins (HIS) in ASCVD. All the lastest meta-analysis included low/moderated intensity statins + ezetimibe versus high intensity statins.•MIS+EZT achieved greater LDL reduction than HIS.•There were no signifficant difference in incidence of MACE between the groups.•More patients achieved LDL goal (
ISSN:1933-2874
DOI:10.1016/j.jacl.2024.07.013