Anti N-methyl-D-aspartate receptor encephalitis during pregnancy: A case report

•The NMDAR encephalitis is an immune-mediated disease characterized by a neuropsychiatric syndrome.•Its predominantly psychiatric symptomatology can lead to diagnostic challenges.•In 50 % of cases, immunoglobulin are combined with corticosteroids.•The balance benefits/risks of oophorectomy during pregnancy has to be considered. Anti-N-methyl-D-aspartate receptor (NMDA-R) encephalitis is an immune-mediated encephalitis that primarily affects young women. Due to the psychiatric and neurological symptoms, the diagnosis can be challenging, especially during pregnancy. During pregnancy, treatments must take into account the fetal and neonatal risk and the risk of premature delivery. We report a case of anti-NMDA encephalitis in a 31-years-old, 30 weeks pregnant women characterized by predominantly psychiatric symptoms, associated with ovarian teratoma. First-line treatments have led to an improvement in symptoms, allowing the pregnancy to be carried to term and a vaginal delivery.