nano-TiO2 reduces bioavailability and biotransformation responses to crude oil WAF-associated PAHs in the European sea bass Dicentrachus labrax

The present study investigates the potential interaction between nano‑titanium dioxide (nano-TiO2) and the water accommodated fraction (WAF) of crude oil and associated chemicals on bioavailability and biotransformation responses in the European sea bass (Dicentrarchus labrax). An in vivo (48-h) wat...

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Veröffentlicht in:Marine pollution bulletin 2024-12, Vol.209 (Pt B), p.117265, Article 117265
Hauptverfasser: Vannuccini, M.L., Della Torre, C., Grassi, G., Zambonin, C., Cotugno, P., Leaver, M.J., Corsi, I.
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Sprache:eng
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Zusammenfassung:The present study investigates the potential interaction between nano‑titanium dioxide (nano-TiO2) and the water accommodated fraction (WAF) of crude oil and associated chemicals on bioavailability and biotransformation responses in the European sea bass (Dicentrarchus labrax). An in vivo (48-h) waterborne exposure with nano-TiO2 (10 mgL−1), crude oil WAF (0.068 gL−1), alone and in combination was performed. Combined exposure significantly reduced levels of polycyclic aromatic hydrocarbons (PAH) in either seawater and fish fillets compared to WAF alone. A significant reduction in the expression of several biotransformation genes (cyp1a, gsta, erβ2, elmod2, abcb1 and abcc1) when nano-TiO2 was combined with WAF was observed in fish liver, compared to WAF alone. EROD and GST enzyme activities were also significantly reduced. Nano-TiO2 can reduce PAHs bioavailability in seawater and biological responses in European sea bass, suggesting a potential safe application of nano-TiO2 for the remediation of crude oil WAF in the marine environment. •nano-TiO2 interact with crude oil WAF-associated PAHs of WAF in seawater.•nano-TiO2 significantly reduce PAHs concentration and bioavailability in seawater.•Biotransformation genes and enzymes in liver of European sea bass juveniles are affected.•nano-TiO2 reduce PAHs biotransformation responses in liver of European sea bass.
ISSN:0025-326X
1879-3363
1879-3363
DOI:10.1016/j.marpolbul.2024.117265