Magnetic field effect upon albumin immobilization

Copolymers of methyl methacrylate (MMA) with 2, 3 epoxypropyl methacrylate (GMA) were tested as matrices for the coupling of the bioactive products. The preparation of polymeric matrices was realized by classic emulsion polymerization (CW) and also comparatively obtained through unconventional procedure in the presence of a magnetic field (MF) of 1500 Gs intensity. As tensioactive substance beta-cyclodextrin was used owing to the future biomedical application of the polymeric matrices. In the paper, the albumin (BSA) adsorption onto the synthesised polymeric matrices, it was study. Thus, it was compared the coupling process performed with or without the magnetic field presence. It was also studied the influence of the temperature upon the albumin adsorption yield. The yield of BSA adsorption is higher in case of the copolymers matrices synthesised in the MF presence. At the same time the BSA adsorption performed in the MF presence evidences decreased yields of coupling. For the polymeric system taken into study, the optimum temperature that allows the albumin adsorption at the most higher amount it was determined as being 30 deg C.