Temperature guided high and very high-power short duration ablation for atrial fibrillation treatment - The peQasus multicentre study

Temperature-controlled high-power short-duration (HPSD) radiofrequency catheter ablation for pulmonary vein isolation (PVI) utilizing a novel ablation catheter (QDOT Micro) with real-time assessment of catheter tip temperature aims for safer, more effective and faster procedures. The peQasus study i...

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Veröffentlicht in:Europace (London, England) England), 2024-11
Hauptverfasser: Heeger, Christian-Hendrik, Almorad, Alexandre, Scherr, Daniel, Szegedi, Nándor, Baran, Jakub, Duytschaever, Mattias, Gupta, Dhiraj, Linz, Dominik, Lyan, Evgeny, Leventopoulos, Georgios, Popescu, Sorin Stefan, Rauber, Martin, Kollias, Georgios, Niedzwiedz, Michał, Sarkozy, Andrea, Badoz, Marc, Sohns, Christian, Ginks, Matthew R, Pürerfellner, Helmut, Tilz, Roland R
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Sprache:eng
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Zusammenfassung:Temperature-controlled high-power short-duration (HPSD) radiofrequency catheter ablation for pulmonary vein isolation (PVI) utilizing a novel ablation catheter (QDOT Micro) with real-time assessment of catheter tip temperature aims for safer, more effective and faster procedures. The peQasus study is a large European multicenter study set up to assess safety, acute efficacy and outcomes of temperature-controlled HPSD based PVI. The primary endpoints were safety, efficacy and 12-months freedom from atrial tachyarrhythmias. Additionally, two strategies namely very HPSD (90W for 4 seconds) only and a hybrid approach (HPSD with maximum of 50W and vHPSD) were compared. A total of 1,023 AF patients in 15 centers from 9 European countries received PVI with the QDOT. Complete PVI was successfully achieved in all patients. In 699/1023 (68.3%) the vHPSD only approach (vHPSD group) and in 324/(31.7%) patients the hybrid approach (hybrid group) was utilized. The mean procedure duration was 98.4±37.4 min (vHPSD: 88.2±34.9min, hybrid: 117.4±32.7min, p
ISSN:1099-5129
1532-2092
1532-2092
DOI:10.1093/europace/euae284