Chemomobilisation Using Gemcitabine-Oxaliplatin for Salvage High Dose Chemotherapy and Autologous Stem Cell Transplant in Advanced Testicular Germ Cell Cancer

Chemomobilisation Using Gemcitabine-Oxaliplatin for Salvage High Dose Chemotherapy and Autologous Stem Cell Transplant in Advanced Testicular Germ Cell Cancer

•At relapse, testicular germ cell tumors may be treated with high-dose chemotherapy and autologous stem cell transplant.•Traditional chemomobilisation protocols for autologous stem cell transplant may be unsuitable for pretreated patients.•Gemcitabine and Oxaliplatin provides satisfactory stem cell...

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Veröffentlicht in:Clinical genitourinary cancer 2024-12, Vol.22 (6), p.102234, Article 102234
Hauptverfasser: McKenzie, Jane, Conduit, Ciara, Hing, Melissa Ng Liet, Zlatic, Kristina, Stokes, Kerrie, Disney, Sharlea, Khot, Amit, Harrison, Simon J., Lewin, Jeremy, Tran, Ben
Format: Artikel
Sprache:eng
Schlagworte:
Germ cell tumors
High-dose chemotherapy
Salvage treatment
Stem-cell transplant
Testicular cancer
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Zusammenfassung:•At relapse, testicular germ cell tumors may be treated with high-dose chemotherapy and autologous stem cell transplant.•Traditional chemomobilisation protocols for autologous stem cell transplant may be unsuitable for pretreated patients.•Gemcitabine and Oxaliplatin provides satisfactory stem cell mobilization and treatment outcomes for this high-risk group.
ISSN:1558-7673
1938-0682
1938-0682
DOI:10.1016/j.clgc.2024.102234