Presence and extent of lymphovascular invasion in surgical stage I squamous cell carcinoma of the cervix: a comprehensive, international, multicentre, retrospective clinicopathological study

The aim of this study was to determine whether the presence and extent of lymphovascular invasion (LVI) is prognostic in surgical stage I cervical squamous cell carcinoma (SCC). All available tumour slides and/or paraffin blocks from 426 patients with stage I cervical SCC treated surgically with cur...

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Veröffentlicht in:	Pathology 2025-02, Vol.57 (1), p.17-26
Hauptverfasser:	Stolnicu, Simona, Allison, Douglas, Tessier-Cloutier, Basile, Momeni-Boroujeni, Amir, Hoang, Lien, Ieni, Antonio, Felix, Ana, Terinte, Cristina, Pesci, Anna, Mateoiu, Claudia, Hodgson, Anjelica, Guerra, Esther, de Brot, Louise, Lastra, Ricardo R., Kiyokawa, Takako, Ali-Fehmi, Rouba, Kheil, Mira, Dundr, Pavel, Roma, Andres, Fadare, Oluwole, Turashvili, Gulisa, Oliva, Esther, Devins, Kyle M., Baiocchi, Glauco, Cibula, David, Soslow, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Cervix Uteri - pathology Cervix Uteri - surgery Female Humans lymph node metastasis Lymphatic Metastasis - pathology lymphovascular invasion Middle Aged Neoplasm Invasiveness Neoplasm Staging Prognosis Retrospective Studies squamous cell carcinoma stage Uterine Cervical Neoplasms - mortality Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - surgery
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Zusammenfassung:	The aim of this study was to determine whether the presence and extent of lymphovascular invasion (LVI) is prognostic in surgical stage I cervical squamous cell carcinoma (SCC). All available tumour slides and/or paraffin blocks from 426 patients with stage I cervical SCC treated surgically with curative intent were collected from 18 institutions and retrospectively analysed. Presence and extent of LVI (focal
ISSN:	0031-3025 1465-3931 1465-3931
DOI:	10.1016/j.pathol.2024.07.008