High- versus low-dose ketamine for analgesia in older adults in the emergency department

Ketamine is increasingly being utilized in the management of acute pain in the emergency department (ED), including for older adults, a population at increased risk of adverse effects from medications. We aimed to compare the safety and analgesic effects of high-dose (≥0.3mg/kg) to low-dose (

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Bibliographische Detailangaben
Veröffentlicht in:	The American journal of emergency medicine 2024-12, Vol.86, p.120-124
Hauptverfasser:	Ginsburg, Alexander D., Heaton, Heather A., Beaudrie-Nunn, Aeryana, e Silva, Lucas Oliveira J., Canterbury, Elizabeth, Brown, Caitlin S., Palmer, Allyson K., Cole, Kristin C., Wieruszewski, Erin D., Bellolio, Fernanda
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Pain - drug therapy Aged Aged, 80 and over Analgesia Analgesics Analgesics - administration & dosage Analgesics - therapeutic use Anesthesia Antiemetics Benzodiazepines Data collection Dose-Response Relationship, Drug Drug addiction Drug dosages Electronic health records Emergency medical care Emergency Service, Hospital Female Humans Intubation Ketamine Ketamine - administration & dosage Ketamine - adverse effects Ketamine - therapeutic use Male Middle Aged Narcotics Older people Pain Pain management Pain Management - methods Pain Measurement Pain perception Patients Retrospective Studies Side effects Substance use
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Beschreibung
Zusammenfassung:	Ketamine is increasingly being utilized in the management of acute pain in the emergency department (ED), including for older adults, a population at increased risk of adverse effects from medications. We aimed to compare the safety and analgesic effects of high-dose (≥0.3mg/kg) to low-dose (
ISSN:	0735-6757 1532-8171 1532-8171
DOI:	10.1016/j.ajem.2024.10.015