Pregnancies at advanced maternal age

The definition of advanced maternal age (AMA) is debated, with an increasing risk of complications from the age of 35, but a threshold of 40 years old is adopted internationally to adjust surveillance and set the term of delivery between 39 and 40 weeks. Patients with AMA have more comorbidities, such as type 2 diabetes and chronic arterial hypertension. They are at greater risk of miscarriage, -gestational diabetes, hypertensive, thrombotic and psychiatric complications, as well as caesarean sections, placenta previa and placental abruption. Additionally, fetal and neonatal complications can occur, including genetic anomalies, fetal growth issues, stillbirths, and prematurity. AMA is a non--modifiable risk factor that must be taken into account to ensure a safe peri-natal period.