The impact of artificial intelligence on the knowledge, attitude, and practice of pharmacists across diverse settings: A cross-sectional study

[Display omitted] •Pharmacists in the Middle East show readiness to embrace AI in pharmacy practice but require additional education and training.•Positive attitudes towards AI integration align with the broader trend of technology adoption in healthcare.•AI’s impact on various pharmacy specialties, including pharmaceutical statistics and pharmacoeconomics, is recognized.•Digital resources, social media, and evidence-based references play a crucial role in pharmacists’ information access.•Educational training programs are essential to bridge the gap between willingness and practical AI readiness in pharmacy practice. The pharmacy practice landscape is undergoing a significant transformation with the increasing integration of artificial intelligence (AI). As essential members of the healthcare team, pharmacists’ readiness and willingness to adopt AI technologies is critical. This cross-sectional study explores pharmacists’ knowledge, attitudes, and practices (KAP) regarding AI in various practice settings. Utilizing a descriptive survey methodology, we collected data through a structured questionnaire targeting pharmacists across diverse working environments. Statistical analyses were conducted to calculate KAP scores. Results revealed that 44.8 % of participants possessed a moderate level of knowledge about AI, while 49.1 % expressed positive attitudes toward its potential applications in pharmacy. However, their current practices related to AI were rated as adequate (57.3 %). Notably, a significant association was found between knowledge, attitudes, and practices (p