Modelling the epidemiological impact of maternal respiratory syncytial virus (RSV) vaccination in Australia

Modelling the epidemiological impact of maternal respiratory syncytial virus (RSV) vaccination in Australia

Respiratory syncytial virus (RSV) is a leading cause of respiratory illness among infants. A maternal RSV vaccine that protects young infants has recently been approved for registration in Australia. We estimated the population benefits of a future year-round maternal RSV vaccination program in term...

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Veröffentlicht in:Vaccine 2024-12, Vol.42 (26), p.126418, Article 126418
Hauptverfasser: Nazareno, Allen L., Newall, Anthony T., Muscatello, David J., Hogan, Alexandra B., Wood, James G.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Age
Age groups
Antibodies
Australia - epidemiology
Babies
Calibration
Child, Preschool
Disease prevention
Effectiveness
Epidemiology
Female
Hospitalization
Hospitalization - statistics & numerical data
Households
Humans
Infant
Infant, Newborn
Infants
Infections
Male
Maternal vaccination
Mathematical modelling
Mother-offspring interactions
Mothers
Older people
Population decline
Pregnancy
Respiratory syncytial virus
Respiratory Syncytial Virus Infections - epidemiology
Respiratory Syncytial Virus Infections - prevention & control
Respiratory Syncytial Virus Vaccines - administration & dosage
Respiratory Syncytial Virus Vaccines - immunology
Respiratory Syncytial Virus, Human - immunology
RSV
Transmission
Vaccination - statistics & numerical data
Vaccine Efficacy
Vaccines
Womens health
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Beschreibung
Zusammenfassung:Respiratory syncytial virus (RSV) is a leading cause of respiratory illness among infants. A maternal RSV vaccine that protects young infants has recently been approved for registration in Australia. We estimated the population benefits of a future year-round maternal RSV vaccination program in terms of prevented RSV infections and hospitalisations in Australia. We described RSV transmission using an age-structured compartmental model calibrated to Australian aggregated monthly RSV-coded hospitalisations in children aged
ISSN:0264-410X
1873-2518
1873-2518
DOI:10.1016/j.vaccine.2024.126418