Exposure, spatial distribution, and health risks of perfluoroalkyl acids in commercial fish species in the Beibu Gulf

The global distribution, persistence, bioaccumulation, and toxicity of per- and polyfluoroalkyl substances (PFAS) have received significant attention. We determined the contents of major perfluoroalkyl acids (PFAAs) in various commercial fish species from different regions of the Beibu Gulf. We detected 14 out of 17 PFAAs across all species, with PFOS (Perfluorooctanesulphonate) showing the highest detection rate, followed by PFHxS (Perfluorohexanesulfonic acid), PFPeA (Perfluorovaleric acid), and PFTrDA (Perfluorotetradecanoic acid). The concentrations of ∑PFAAs ranged from 0.22 to 7.43 ng/g (ww). Additionally, PFCAs dominated the PFAA profile (70 %) in the southern Beibu Gulf in comparison with the northern (53 %) and central Beibu Gulf (48 %). PFOS was the most abundant compound, accounting for 41 % of total PFAAs, followed by PFUdA (Perfluoroundecanoic Acid) (14 %) and PFOA (Perfluorooctanoic Acid) (12 %). The estimated daily intakes and hazard ratios of PFOS and PFOS indicate that there is no significant health risk from people consuming these fish. •Perfluoroalkyl acids of common consumed fish species from Beibu Gulf were detected.•PFAAs are dominated by PFOS, and long chain PFAAs are dominant.•There are spatial differences in PFAA profiles in Beibu Gulf.•There is no health risk for PFOA and PFOS in common fish in the Beibu Gulf region.