Synthesis and structural confirmation of selaginpulvilin X

We report the first total synthesis of the natural product selaginpulvilin X, a selaginellaceae polyphenol class of compounds. Our synthetic strategy employs cross-coupling reactions and an organolithium addition to construct the carbon framework. Subsequently, the functional group modifications and deprotection yield the natural product. Spectral analysis confirms the proposed structure by comparing natural and synthetic samples. We report the first synthesis of natural product selgunpulvilin X, isolated recently from selaginalla pulvinata .