Comparative analysis of dietary patterns in patients with non-alcoholic fatty liver disease with and without type 2 diabetes mellitus

Non-alcoholic fatty liver disease (NAFLD) is considered to be metabolically determined and alimentary condition, one of the components of metabolic syndrome. Therefore, dietary patterns of patients with different clinical types of the disease are worth to be studied . of the research was to study th...

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Veröffentlicht in:Problems of Nutrition 2024, Vol.93 (4), p.92-103
Hauptverfasser: Sasunova, A N, Goncharov, A A, Isakov, V A
Format: Artikel
Sprache:eng ; rus
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Zusammenfassung:Non-alcoholic fatty liver disease (NAFLD) is considered to be metabolically determined and alimentary condition, one of the components of metabolic syndrome. Therefore, dietary patterns of patients with different clinical types of the disease are worth to be studied . of the research was to study the dietary patterns in patients with NAFLD and with type 2 diabetes mellitus (T2DM) (group T2DM+) compared to the control group without T2DM (T2DM-). . A retrospective analysis of the database (n=316) of patients with NA FLD, formed in the period from 202 1 to 2023, was carried out. A total of 79 sex- and agem atched pairs of T2D+ and T2D- pat ients were selected for the case-control study. Hepatic steatosis and fibrosis stage assessment was performed using vibration-controlled transient elastography (VCTE) with controlled attenuation parameter (CAP). Actual nutrition was evaluated using a semi-quantitative method of assessing consumption frequency during a personal interview. Consumption of 100 grouped food items was assessed. Blood parameters characterizing lipid and carbohydrate metabolism were assessed. . Among patients with T2DM+, patients with NASH (24.1 vs 8.9%, p=0.005) and patients with severe liver fibrosis F3-F4 (32.9 vs 10.1%, p
ISSN:0042-8833
2658-7440
DOI:10.33029/0042-8833-2024-93-4-92-103