Genetic African ancestry modifies the biology of acute myeloid leukemia

African American patients were under-represented in the studies that led to the current patient classification system for acute myeloid leukemia (AML). A new in-depth analysis of the genetics of AML in African Americans suggests that this omission has implications for patient care.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature genetics 2024-11, Vol.56 (11), p.2299-2301
1. Verfasser:	Jiagge, Evelyn M.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/212/2019 631/208/514/1948 631/67/1059/602 631/67/1990/283/1897 Acute myeloid leukemia African Americans Agriculture Animal Genetics and Genomics Biology Biomedical and Life Sciences Biomedicine Cancer Cancer Research Classification Clinical trials Gene Function Genetics Human Genetics Leukemia Medical prognosis Mutation News & Views news-and-views Patients Self report Tumors
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Beschreibung
Zusammenfassung:	African American patients were under-represented in the studies that led to the current patient classification system for acute myeloid leukemia (AML). A new in-depth analysis of the genetics of AML in African Americans suggests that this omission has implications for patient care.
ISSN:	1061-4036 1546-1718 1546-1718
DOI:	10.1038/s41588-024-01869-6