PRC2-RNA interactions: Viewpoint from Jimmy K. Guo, Mario R. Blanco, and Mitchell Guttman

Many reported PRC2-RNA interactions have been shown to be functionally dispensable, raising questions about whether they occur in vivo. Here, we lay out technical issues with existing evidence for direct binding and argue that there is currently a lack of biochemical or functional evidence for direc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular cell 2024-10, Vol.84 (19), p.3578-3585
Hauptverfasser:	Guo, Jimmy K., Blanco, Mario R., Guttman, Mitchell
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Humans Polycomb Repressive Complex 2 - genetics Polycomb Repressive Complex 2 - metabolism Protein Binding RNA - genetics RNA - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!