RNAs kiss and translate in germ granules

RNAs kiss and translate in germ granules

The assembly of germ granules remains unknown, but recent attention to the role of RNA structure in membrane-less organelle assembly is changing our understanding of RNAs in the cell. Two studies now show how RNA–RNA interactions drive germ granule assembly and how germ granules spatially regulate e...

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Veröffentlicht in:Nature cell biology 2024-11, Vol.26 (11), p.1828-1829
Hauptverfasser: Jalihal, Ameya P., Geisterfer, Zachary M., Gladfelter, Amy S.
Format: Artikel
Sprache:eng
Schlagworte:
631/80
631/80/642
Assembly
Biology
Biomedical and Life Sciences
Cancer Research
Cell Biology
Developmental Biology
Granular materials
Insects
Life Sciences
Localization
mRNA
News & Views
news-and-views
Proteins
Roles
Stem Cells
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Beschreibung
Zusammenfassung:The assembly of germ granules remains unknown, but recent attention to the role of RNA structure in membrane-less organelle assembly is changing our understanding of RNAs in the cell. Two studies now show how RNA–RNA interactions drive germ granule assembly and how germ granules spatially regulate embryonic mRNA translation.
ISSN:1465-7392
1476-4679
1476-4679
DOI:10.1038/s41556-024-01502-y